How does it work? Alprostadil is the same as a naturally occurring chemical called prostaglandin E1. This prostaglandin is thought to cause some types of blood vessels to widen by relaxing the thin layer of muscle found in the vessel wall. An erection is produced via a complex chain of events, involving signals from the nervous system and the release of active chemicals, including prostaglandin E1 within the tissues of the penis. These chemicals cause blood vessels entering the penis to widen, allowing more blood to enter. They also cause less blood to leave the penis. Prostaglandin E1 plays an important role in this process and alprostadil, when administered directly into the penis, will ultimately cause the penis to become rigid and erect by increasing the blood flow into its tissues. This preparation is administered by injection directly into the penis. What is it used for? Aid to diagnosis of erectile dysfunction Impotence (erectile dysfunction).
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