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Sildenafil Citrate is basically a medical word for the drug that is used to cure erectile dysfunction. Although there are many resemblances in the naming arrangement but the actual drug is quite different. The genuine form of this drug is very expensive and most of the time it is sold in very small amount. Generally, sildenafil citrate is considered as one of the most effective and reasonable steroid for erectile dysfunction.

Working of Sildenafil Citrate

Through the early phase of stimulation in males, there are various hormonal excretions that are occurred in the human body. cGMP is one of those excretions, it has the responsibility to transmit motions from the brain to the boundary of the body that creates an instantaneous blood stream gust to the penis. All the muscles related with penis are relaxed, which makes the blood stream rush into the penis that makes it erected. For the purpose of successful erections, cGMP nucleotide is in control and this is the main thing that causes erectile dysfunction in males. As the accurate signals are not transmitted from the brain to most part of the body, therefore a man cannot get full erection. This steroid is considered as one of the most powerful and effective drug that is used in order to respond to the erectile dysfunction problem. Individuals who are willing to erect their penis and perform sex for longer period of time are recommended to use Sildenafil Citrate in normal dose.

Recommended Dose of Sildenafil Citrate

The first time users are suggested to take this steroid under the prescription of any doctor or physician because they can provide proper dose after analyzing the patients’ medical condition and past history with steroids and how sildenafil citrate is going to react on the body. Individuals are suggested to consume this steroid at least 1 hour before engaging and any kind of sexual activity and they should not consume it more than one time in a day.

Since many males are experiencing the embarrassing problem of erectile dysfunction, so for those people sildenafil citrate is highly recommended as it can provide full and powerful erection. Sildenafil citrate works as a natural restorative that enhances the blood stream in the manly body part that certifies that the penis gets fully erect.

Side Effects of Sildenafil Citrate

Similarly, like any other steroid, sildenafil citrate also contains some of the side effects that the individuals must understand before taking this steroid. These side effects are minor and goes away after few hours of using. The widely known side effects of this steroid are dizziness, rashes, nuisances, upset stomach and nose strictness. The individuals most not consume any alcohol with sildenafil citrate as it can cause extreme side effects. Sometimes higher doses of this steroid can cause some serious side effects. So in order to avoid these side effects, any individual must consult a doctor, physician or any other medical professional about the suitable dose before taking sildenafil citrate.

 
 

Sildenafil citrate – treatment for erectile dysfunction. Restores the broken erectile function and provides natural response to sexual arousal.Sildenafil is a potent and selective inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5), which is responsible for the collapse of cGMP in the cavernous body. Sildenafil has no direct relaxing effect on the cavernous body but actively enhances the relaxing effect of nitric oxide in this tissue. During sexual arousal local release of NO under the influence of sildenafil leads to the inhibition of PDE5 and increased levels of cGMP in the cavernous body, this results in smooth muscle relaxation and increased blood flow in the cavernous body.

Sildenafil may cause mild and transient violation of distinguishing colors (blue/green). Alleged violations of the mechanism of color vision is the oppression PDE, which is involved in the transmission of light in the retina. In vitro studies have shown that the effect of sildenafil on PDE 10 times inferior to its activity against PDE5.

In vitro studies indicate that the activity of sildenafil against PDE5 in 10-10000 times higher activity against other isoforms of the phosphodiesterase (PDE 1, 2, 3, 4 and 6). In particular, the activity of sildenafil against PDE5 4000 times greater than its activity against PDE – camp-specific phosphodiesterase involved in the contraction of the heart.

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