Clonazepam antiepileptic drug from the group of benzodiazepine derivatives. Has a pronounced anticonvulsant and Central muscle relaxant, anxiolytic, sedative and hypnotic effect.
Enhances the inhibitory effect of GABA on the transmission of nerve impulses. Stimulates benzodiazepine receptors located in the allosteric center of postsynaptic GABA-receptor activating ascending reticular formation of the brainstem of neuronal inserted horns lateral spinal cord. Decreases anxiety subcortical structures of the brain (limbic system, thalamus, hypothalamus), inhibits the postsynaptic spinal reflexes.
Anxiolytic effects due to the influence of amygdaloid complex of the limbic system and is manifested in the reduction of emotional stress, weakening of anxiety, fear, worry.
Sedation due to the influence of the reticular formation of the brain stem and the nonspecific nuclei of the thalamus and is manifested by a decrease in neurotic symptoms (anxiety, fear).
Anticonvulsant action is realized by increasing presynaptic inhibition. Thus there is suppression of epileptic activity spreading occurring in epileptogenic foci in the cortex, thalamus and limbic structures, but not removed the excited state of the hearth.
It was shown that in humans, clonazepam rapidly suppresses the paroxysmal activity of different types, including the complex “spike-wave” absansah (petit mal), slow and generalized complexes “spike-wave”, “spikes” and other temporal localization, as well as occasional “spikes” and wave.
Changes in the EEG of generalized type are suppressed to a greater extent than focal. In accordance with these data clonazepam has beneficial effects in generalized and focal forms of epilepsy.
Central muscle relaxant effect is due to inhibition of spinal polysynaptic afferent paths of the brake (to a lesser extent and monosynaptic). It is possible, and direct inhibition of motor nerves and muscle function.
Always follow the prescription and dosage amount that your doctor recommends. Klonopin regularly comes in two different forms: wafer and tablet.
If your doctor has prescribed you the wafer, which is an orally dissolving tablet, then you should remove the tablet right before consumption. When removing the tablet from the package, make sure that your hands are completely dry. Place the tablet on your tongue so it can dissolve instantly.
Otherwise, if your doctor prescribes you the tablet form, you should swallow the entire tablet with a glass of water. In most cases, your doctor will only prescribe this medication for 9 weeks, so take as directed.
Drowsiness, dizziness, tiredness, loss of coordination, or increased saliva production may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
A small number of people who take anticonvulsants for any condition (such as seizures, bipolar disorder, pain) may experience depression, suicidal thoughts/attempts, or other mental/mood problems. Tell your doctor right away if you or your family/caregiver notice any unusual/sudden changes in your mood, thoughts, or behavior, including: confusion, memory problems, signs of depression, suicidal thoughts/attempts, thoughts about harming yourself.
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